Microbiologics, a leading Infectious Disease Contract Research Organization:

• Aids in developing life-saving antibiotics, antivirals, vaccines, and diagnostic technologies.
• Recognizes unique challenges in each research projects and provides tailored solutions.
• Is experienced in working with a broad portfolio of BSL-2 and BSL-3 pathogens, including SARS-CoV-2, Influenza A & B, Mycobacteria, and Chlamydia spp.

As the global health community continues to grapple with the rise of infectious diseases and antimicrobial resistance, the demand for cutting-edge research and development in anti-infective agents has never been greater. Microbiologics, a leading Infectious Disease Contract Research Organization (CRO), is playing a pivotal role in this fight by providing scientists worldwide with the necessary resources and expertise to develop life-saving antibiotics, antivirals, vaccines, and diagnostic technologies.

Microbiologics recognizes that each research project comes with its own unique challenges. The company's consultative approach ensures close collaboration with partners, offering tailored solutions that address specific needs. With extensive experience working with a broad portfolio of BSL-2 and BSL-3 pathogens, such as SARS-CoV-2, Influenza A & B, Mycobacteria, and Chlamydia spp., Microbiologics stands out as an invaluable partner in advancing scientific research.

Cutting-Edge Antiviral Testing
Microbiologics offers a broad array of in vitro antiviral testing services. From standardized, off-the-shelf assays to fully customized, multifaceted testing programs, Microbiologics is committed to supporting pharmaceutical and academic researchers in their quest to discover novel, life-changing antiviral agents and vaccines. The company’s comprehensive antiviral testing services include: Hemagglutination Inhibition (HAI), Neuraminidase Inhibition (NAI), Microneutralization (MN), Viral Load (TCID₅₀  and qPCR/ddPCR) and beyond, providing researchers with the reliable and actionable data they need.

Understanding that antiviral research often requires unique solutions, Microbiologics stays at the forefront of assay technology, incorporating the latest advancements to deliver cutting-edge and customizable solutions. Their team of scientists possess deep virological expertise and are adept at designing and optimizing assay programs for a wide range of viruses. They are also skilled in technology transfers to facilitate the passing of knowledge, documentation, and protocols between their laboratories and the clients'.

Advanced Antibacterial and Antifungal Testing
As a leading CRO, Microbiologics supports the discovery, development and registration of new antimicrobial agents with a broad portfolio of antibacterial and antifungal testing and consulting services. The company’s Antimicrobial and Microbiome Research Center maintains a biobank of over 12,000 clinical pathogens including strains with characterized resistance which is available for extensive screening. With a highly knowledgeable and experienced team of scientists, Microbiologics provides high-throughput screening and susceptibility testing, lead characterization studies, test method development and evaluation, and consulting for IND/NDA submission.

Microbiologics has specialized expertise in cell-based anti-infective assays including Intracellular Killing, MTT Toxicity, and MIC testing of Chlamydia spp. The company recently expanded their capabilities to offer OPKA and SBA assays, supporting vaccine development for bacterial and fungal targets. Additional services that support the development of microbiome products and therapeutics include LBP characterization, enumeration, antibiogram analysis, evaluation of pre- and probiotics on growth kinetics of indicator organisms in co-culture, and metagenomics.

Reliable Viral and Microbial RUO Stocks
Beyond testing services, Microbiologics offers a comprehensive range of viral and microbial RUO stocks, meticulously crafted to meet the diverse needs of researchers across drug and vaccine development, diagnostic assay development, and academic research. Whether researchers require off-the-shelf, ready-to-ship materials or custom-designed solutions, Microbiologics provides materials boasting the highest titers in both live and inactivated formats. These expertly prepared reference materials are essential for achieving the accuracy and reproducibility that advanced research demands.

Custom Virus Stock Manufacturing
Microbiologics offer the most extensive customization options for virus production, ensuring their partners receive a final product that meets their specific needs. With a team of approachable experts, Microbiologics collaborates with their clients to provide guidance where and when they need it throughout each project. Their state-of-the-art facilities, combined with advanced technologies and a highly skilled team, allow them to customize virtually any aspect of the virus stock production process from choice of host cells and culture conditions to purification, titration, inactivation or attenuation. The company is known for their expertise in both cell-based and egg-based propagation of viruses. Additionally, they offer reverse genetics services, enabling intentional modifications to existing genes or the introduction of new genes not typically found in the virus.

High-Titer Off-The-Shelf Virus Stocks
Microbiologics off-the-shelf virus stocks provide convenience and reliability. With an extensive collection readily available for immediate shipment, clients gain swift access to the strains they need to keep their projects moving forward. Microbiologics virus stocks boast the highest titers and copy numbers in the industry, ensuring optimal performance in drug research and diagnostic assay development applications. Scientists can confidently advance their work with Microbiologics' off-the-shelf virus stocks at their fingertips. From household names like Influenza to emerging threats like Dengue, Microbiologics works with a broad portfolio of infectious agents.

Custom Microbial Stock Manufacturing
Microbiologics offers comprehensive custom microbial manufacturing services for bacteria, fungi, parasites, phage, and nucleic acids, providing tailored solutions to meet specific research challenges. The company offers various preservation methods for bacteria and fungi, including lyophilized and liquid formats, and can produce both qualitative and quantitative materials. Their phage services include custom-grown MS-2, T4, T7, and Phi X174, available in various purities and concentrations. Additionally, Microbiologics specializes in nucleic acid formats for diagnostic and pathogen detection, including gDNA, plasmid/synthetic DNA, and total RNA, with target copy numbers tailored to specific needs.

High-Titer Off-The-Shelf Microbial Stocks
Microbiologics offers high-titer, heat-inactivated RUO microbial stocks that are essential for diagnostic assay development as well as drug and vaccine research and development. Available off-the-shelf, these microbial stocks provide the precise genetic targets that assay developers need to ensure diagnostic accuracy and reliability. The high-titer, high genome copy number material also play a critical role in supporting the research and development processes for new drugs and vaccines, offering unmatched convenience and reliability to researchers committed to advancing healthcare.

Partnering for a Safer, Healthier Future
The demand for accurate and reproducible antiviral, antibacterial, and antifungal testing services is expanding rapidly. In response, Microbiologics continuously reviews its capabilities and assesses market needs to ensure long-term support for its partners. Infectious diseases caused by viruses and bacteria remain significant threats to public health, making accurate testing crucial for diagnosing infections, determining appropriate treatments, and tracking disease spread.

Microbiologics' highly trained and flexible team is equipped to handle unique compounds, testing procedures, and pathogens that are often challenging to grow or test. The company is committed to staying ahead of the technology and industry advancements, anticipating partner needs, and ensuring that capacity and resources are available to support the development of new technologies and treatments. With a focus on custom requests, Microbiologics offers a level of flexibility that surpasses other infectious disease CROs. The team takes a consultative approach, collaborating closely with partners to build custom programs tailored to their specific requirements, fostering a history of overcoming challenges and advancing alongside their customers.

Visit Microbiologics.com to learn more or request a custom quote.