As a novel pathogen identification technique, next-generation metagenomic sequencing (mNGS) isa pwerful new tool able to recognise bacteria, viruses, fungi, parasites, rare pathogens, and even unknown pathogens. Able to identify all nucleic acids in a sample even ones that contain mixed populations. The NGS method is unbiased, able to quickly, effectively, and precisely extract all nucleic acid information from a sample, and is thus perfectly suited for examining potentially pathogenic microbes.

However, false positives can be an issue throughout the mNGS testing procedure resulting from trace DNA contaminants found in lab reagents, centrifuge tubes, or other phases of the experimental workflow that can contaminate the DNA.

VDOBIOTECH now offers magnetic beads for nucleic acid extraction along with other solutions to meet customer needs and address the issue of background microbial contamination during the pre-processing of mNGS sequencing samples. As a result, the problem of microbial contamination linked to magnetic beads is effectively solved, preventing result misunderstanding and improving the accuracy of mNGS testing findings.

VDOBIOTECH Magnetic Bead Background Bacterial Contamination Removal Scheme Demonstration