Charles River Unveils Endosafe®-PTS™ Glucan Assay

Charles River has introduced a new test to help ensure that your products are as free of contaminants as possible. Recent inspections have indicated a need to verify the absence of glucans. The Endosafe®-PTS™ glucan assay is a rapid test designed for investigational purposes to validate that your products are free of (1,3)-b-D glucans.

(1,3)-b-D glucan molecules can be found in the cell walls of most yeasts and molds. These glucans contaminate cell culture fluid, yeast protein production, air quality samples, and cellulose filter preparations. Glucans can cause false positive results in LAL assays triggering OOS investigations.

Charles River's new PTS™ glucan assay allows you to quickly and easily quantify these glucans, leading to better process monitoring and faster OOS resolutions. The Charles River glucan cartridges have a sensitivity range of 10-1,000 pg/ml, yield results in less than 30 minutes, and can be run on the same Charles River PTS™ reader that is used for endotoxin detection and Gram identification.

This new product offering is in addition to the glucan-specific buffer that Charles River already offers for those compounds that you know in advance have a strong possibility of being contaminated by glucans.

For more information about the new Charles River glucan assay or about our line of rapid endotoxin testing products, please call 1.877.CRIVER1 or visit the Glucan page on our website.