Real-Time Test for Detecting Microbial Contamination in Biopharmaceutical Applications
| Millipore Corporation and Gen-Probe have launched the first product from their collaboration to create faster, sensitive, more robust tests for detecting contaminants in pharmaceutical and biotechnology manufacturing processes. The MilliPROBE system is the first solution of its kind for biopharmaceutical manufacturing. It combines Millipore's leading, industry-accepted sample prep methodologies with Gen-Probe's advanced, proven nucleic acid technologies to deliver both speed and sensitivity in one microbial screening tool. The MilliPROBE system uses Real-Time Transcription-Mediated Amplification (TMA) technology to detect targeted microbial contamination within hours compared to the days or weeks usually required to generate results using traditional culture-based technology. The collaboration's first MilliPROBE assay targets the bacterium Pseudomonas aeruginosa and is designed as an in-process, early warning system to provide faster, more effective detection of P. aeruginosa in purified water used during drug production. The assay was designed to ensure a higher degree of water quality throughout manufacturing processes where the contaminant can be a serious quality and safety concern. The components of the MilliPROBE system are developed, manufactured and tested to work together to provide customers a complete solution that generates consistent, dependable results. Building on the technological innovation of the initial MilliPROBE assay, Millipore and Gen-Probe intend to continue to develop new assays for additional contaminants over the next few years. These assays are expected to provide further significant improvements in speed, sensitivity, and specificity and incorporate future sample prep innovations that will allow real-time TMA technology to be applied to more challenging biopharmaceutical applications and target microorganisms. |
NOTE: This item is from our 'historic' database and may contain information which is not up to date.
Source : Millipore Corp View Company Information
Posted on January 15, 2008
Get our eNewsletter
Over 7,000 microbiology professionals get our weekly eNewsletter - subscribe now and find out why!
LATEST MICROBIOLOGY NEWS
- Coming Soon: Home Testing with Liquid and Dry Swabs by MWE
- Breakthrough in qPCR Efficiency: Cut Your PCR Run Time by 75% with MegaMix Emerald qPCR Mastermix
- Fighting Resistance: Innovative Solutions Against Resistant Candida
- Preanalytics in Focus: Choosing the Right Swab, Transport, and Automation
- Consistent Quality for At-home or Point-of-care Swab Testing
- The Evolution of Swabs: From Collection Tools to Active Diagnostic Enablers
- Preanalytics: Choosing The Right Swab, Transport And Automation - a rapidmicrobiology Special Focus
- Transforming Food Safety with Real-Time Results via Mobile
- Addressing Subjective Readings and Manual Workflows in Allergen Testing
- Be Prepared this Season with Puritan® Specimen Collection Supplies
MICROBIOLOGY EVENTS
- Confience Webinar - Steps to Selecting the Right LIMS Partner
- PharmaLab Congress and Exhibition 2024
- Alternative and Rapid Microbiological Methods
- Setting Shelf life: How To Do It Better
- XXII Workshop on Rapid Methods and Automation in Food Microbiology (MRAMA) - DYCFung Memorial
- BOS Manchester 2024
- Optimizing ISO Method Testing with Rapid Solutions
- Saving Time and Money With Alicyclobacillus Rapid Microbiology Method
- 9th Annual Microbiome Movement Summit Europe
- 2025 QC Micro Summit