New CLSI Guideline for Collection, Processing, and Interpretation of Blood Cultures

The prompt and accurate detection of bacteremia and fungemia is one of the most important functions of clinical microbiology laboratories. Guidelines for the collection, processing, and interpretation of blood cultures are needed so that laboratories and providers use optimal laboratory methods for recovering specific pathogens, interpret the results correctly, and help control healthcare costs.

In response to this need, the CLSI has recently published a new document, Principles and Procedures for Blood Cultures; Approved Guideline (M47-A).

This document provides recommendations for the collection, transport, and processing of blood cultures, as well as guidance for the recovery of pathogens from blood specimens taken from patients who are suspected of having bacteremia or fungemia.

Included in the guideline are recommendations for:

• the clinical importance of blood cultures;
  
• specimen collection and transportation;
  
• critical factors in the recovery of pathogens from blood specimens;
  
• special topics, including pediatric blood cultures, catheter-related bloodstream infections, infective endocarditis, patients receiving antimicrobial therapy, rare and fastidious pathogens, and test of cure;
  
• reporting results;
  
• interpreting blood culture results;
  
• safety issues; and
  
• quality assurance.
  

This guideline is intended to provide guidance to clinical microbiologists and other laboratorians (e.g., pathologists, laboratory supervisors, laboratory managers) for the recovery of pathogens from blood specimens taken from patients who are suspected of having bacteremia or fungemia.

For additional information on M47-A click here to visit CLSI website or call +610.688.0100.