A new study conducted by researchers at the John A. Burns School of Medicine, University of Hawaii, evaluated the InBios DENV Detect IgM Capture ELISA for qualitative detection of IgM antibodies to dengue virus recombinant antigens[1]

Well characterized clinical serum samples collected from Hawaii, Vietnam, Niue, Singapore and American Samoa were tested with the DENV Detect IgM Capture ELISA in comparison with in-house DENV IgM antibody capture (MAC) ELISA. The agreement, sensitivity, and specificity of the InBios assay were 94, 92 and 94% respectively. The study found that InBios’ DENV Detect IgM Capture ELISA is advantageous compared to the in-house MAC-ELISA, as the results can be obtained in less than 5 hours, whereas the in-house MAC-ELISA requires 2 to 3 days.

The study, titled “Evaluation of a New Commercially Available Immunoglobulin M Capture Enzyme-Linked Immunosorbent Assay for Diagnosis of Dengue Virus Infection,” was published in the Journal of Clinical Microbiology, July 2013;51(9):3102-6.

This study was supported in part by grants P20GM103516, U01AI078213 and U54MD007584 from the National Institutes of Health, grant W81XWH0720073 from the Department of Defense and by institutional funds.