Most of us realize that the Omicron variant of the SARS-CoV-2 virus possesses multiple mutations in the Spike protein. However this variant also has mutations in the nucleocapsid protein (N) as well.
This is critically important since current antigen tests detect the nucleocapsid by immunoassay. The antibodies employed in these tests must recognize the mutated N antigen otherwise a false negative test will result.
ViroStat has validated their 4 best monoclonal antibody pairs (products #3865-#3868) for reactivity with the nucleocapsid of the Omicron variant. These high affinity antibody pairs are used successfully in lateral flow and ELISA applications for antigen detection of the other variants as well.
Download the updated data sheet for these antibodies at: www.virostat-inc.com
ViroStat is a primary manufacturer, supplying infectious disease reagents to researchers and rapid test manufacturers since 1985.