Dengue fever is a mosquito-borne tropical disease caused by dengue virus types 1-4. Currently, quantitative RT-PCR is the preferred method for the detection and quantification of dengue virus in clinical diagnostics and epidemiological surveillance. To aid in these analyses, ATCC has developed four synthetic molecular standards that represent dengue virus types 1-4.

Each quantified standard contains short fragments from the capsid, membrane, and envelope genes of the dengue virus genome. Moreover, they exhibit minimal variability, have a long shelf life, eliminate the need to culture viruses, and can be used under BSL-1 conditions, making them ideal for a number of applications, including:

• Generation of a standard curve
• Validation and verification studies
• Monitoring assay-to-assay, lot-to-lot, and operator variation

Browse our collection of synthetic viral nucleic acids today! For additional information on the authentication and characterization of synthetic and genomic nucleic acids produced at ATCC, please visit us online at www.atcc.org/genuinenucleics